Role of matrix metalloproteinases 2 and 9, toll-like receptor 4 and platelet-leukocyte aggregate formation in sepsis-associated thrombocytopenia

• Caroline M. Larkin ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: carolinelarkin@gmail.com

  Affiliations Department of Anaesthesia and Intensive Care Medicine, St James’s Hospital, Dublin, Ireland, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

  http://orcid.org/0000-0001-5373-3978

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• Nadhim Kamil Hante ,

  Contributed equally to this work with: Nadhim Kamil Hante, Eamon P. Breen

  Roles Investigation, Methodology

  Affiliations School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland, College of Pharmacy, University of Kufa, Najaf, Iraq

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• Eamon P. Breen ,

  Contributed equally to this work with: Nadhim Kamil Hante, Eamon P. Breen

  Roles Formal analysis, Investigation, Methodology

  Affiliation Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland

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• Krzysztof A. Tomaszewski,

  Roles Investigation, Visualization

  Affiliations School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland, Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland

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• Simon Eisele,

  Roles Investigation

  Affiliation Department of Pharmacy, Ludwig Maximilian University, Munich, Germany

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• Marek W. Radomski,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – review & editing

  Affiliations School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland, School of Medicine, University of Saskatchewan, Saskatoon, Canada

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• Thomas A. Ryan,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Resources, Writing – review & editing

  Affiliations Department of Anaesthesia and Intensive Care Medicine, St James’s Hospital, Dublin, Ireland, School of Medicine, Trinity College Dublin, Dublin, Ireland

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• Maria-Jose Santos-Martinez

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

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