Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction

• John D. Belcher ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: belcher@umn.edu

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  http://orcid.org/0000-0001-5536-2752

  ⨯
• Chunsheng Chen,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Julia Nguyen,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Fuad Abdulla,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Ping Zhang,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Hao Nguyen,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Phong Nguyen,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Trevor Killeen,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Sylvia M. Miescher,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Writing – review & editing

  Affiliation CSL Behring AG, Research and Development, Bern, Switzerland

  ⨯
• Nathan Brinkman,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Writing – review & editing

  Affiliation CSL Behring, Research & Development, Kankakee, Illinois, United States of America

  ⨯
• Karl A. Nath,

  Roles Writing – review & editing

  Affiliation Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Clifford J. Steer,

  Roles Writing – review & editing

  Affiliation Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯
• Gregory M. Vercellotti

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, Division of Hematology, Oncology and Transplantation, Vascular Biology Center, University of Minnesota, Minneapolis, Minnesota, United States of America

  ⨯