Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents and young adults (BREATHER): Extended follow-up results of a randomised, open-label, non-inferiority trial

• Anna Turkova ,

  Roles Investigation, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: a.turkova@ucl.ac.uk

  Affiliations MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom, Paediatric infectious Diseases Department, Great Ormond Street Hospital, London United Kingdom

  http://orcid.org/0000-0002-7008-4145

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• Cecilia L. Moore,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

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• Karina Butler,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Paediatric Department, Our Lady's Children's Hospital, Crumlin, Ireland

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• Alexandra Compagnucci,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Clinical Trials and Infectious Diseases, INSERM/ANRS SC10-US19, Villejuif, France

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• Yacine Saïdi,

  Roles Conceptualization, Data curation, Project administration, Writing – review & editing

  Affiliation Clinical Trials and Infectious Diseases, INSERM/ANRS SC10-US19, Villejuif, France

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• Victor Musiime,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliations Research Department, Joint Clinical Research Center, Kampala, Uganda, Paediatric Department, Makerere University, Kampala, Uganda

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• Annet Nanduudu,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Research Department, Joint Clinical Research Center, Kampala, Uganda

  http://orcid.org/0000-0002-5922-8152

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• Elizabeth Kaudha,

  Roles Investigation, Writing – review & editing

  Affiliation Research Department, Joint Clinical Research Center, Kampala, Uganda

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• Tim R. Cressey,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliations PHPT-IRD UMI 174, Faculty of Associated Medical Sciences, Department of Medical Technology, Chiang Mai University, Chiang Mai, Thailand, Department of Immunology & Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America, Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom

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• Suwalai Chalermpantmetagul,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation PHPT-IRD UMI 174, Faculty of Associated Medical Sciences, Department of Medical Technology, Chiang Mai University, Chiang Mai, Thailand

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• Karen Scott,

  Roles Project administration, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

  http://orcid.org/0000-0001-6459-8468

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• Lynda Harper,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

  http://orcid.org/0000-0003-3430-0127

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• Samuel Montero,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

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• Yoann Riault,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Clinical Trials and Infectious Diseases, INSERM/ANRS SC10-US19, Villejuif, France

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• Torsak Bunupuradah,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation The HIV Netherlands Australia Thailand Research Collaboration, The Thai Red Cross AIDS Research Center, Bangkok, Thailand

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• Alla Volokha,

  Roles Investigation, Writing – review & editing

  Affiliations Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Kyiv City Centre for Prevention and Control of AIDS, Kyiv, Ukraine

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• Patricia M. Flynn,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Infectious Diseases, Saint Jude Children's Research Hospital, Memphis, United States

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• Rosa Bologna,

  Roles Investigation, Writing – review & editing

  Affiliation Epidemiology and Infectious Diseases Department, Hospital de Pediatría Dr JP Garrahan, Buenos Aires, Argentina

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• Jose T. Ramos Amador,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Paediatrics, Hospital Clinico Universitario San Carlos, Madrid, Spain

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• Steven B. Welch,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Paediatrics, Birmingham Heartlands Hospital, Birmingham, United Kingdom

  http://orcid.org/0000-0002-6923-3502

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• Eleni Nastouli,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Virology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

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• Nigel Klein,

  Roles Investigation, Writing – review & editing

  Affiliation Infection, Immunity and Inflammation Programme, University College London Institute of Child Health, London, United Kingdom

  http://orcid.org/0000-0003-3925-9258

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• Carlo Giaquinto,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Paediatrics, University of Padova, Padova, Italy

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• Deborah Ford ,

  Contributed equally to this work with: Deborah Ford, Abdel Babiker, Diana M. Gibb

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

  http://orcid.org/0000-0003-1713-6302

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• Abdel Babiker ,

  Contributed equally to this work with: Deborah Ford, Abdel Babiker, Diana M. Gibb

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

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• Diana M. Gibb ,

  Contributed equally to this work with: Deborah Ford, Abdel Babiker, Diana M. Gibb

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation MRC CTU, University College London Institute of Clinical Trials and Methodology, London, United Kingdom

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•  [ ... ],
• on behalf of the BREATHER (PENTA 16) trial Group

  ¶Membership of the BREATHER (PENTA 16) trial Group is listed in S2 File.

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