The role of SeDeM for characterizing the active substance and polyvinyilpyrrolidone eliminating metastable forms in an oral lyophilizate—A preformulation study

• Paloma Flórez Borges ,

  Contributed equally to this work with: Paloma Flórez Borges, Encarna García-Montoya, Pilar Pérez-Lozano, Albert Manich

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: pflorezb@gmail.com

  Affiliations Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Barcelona. Barcelona, Spain, Reig Jofre Group. Sant Joan Despí, Spain

  http://orcid.org/0000-0002-5122-3410

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• Encarna García-Montoya ,

  Contributed equally to this work with: Paloma Flórez Borges, Encarna García-Montoya, Pilar Pérez-Lozano, Albert Manich

  Roles Formal analysis

  Affiliation Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Barcelona. Barcelona, Spain

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• Pilar Pérez-Lozano ,

  Contributed equally to this work with: Paloma Flórez Borges, Encarna García-Montoya, Pilar Pérez-Lozano, Albert Manich

  Roles Formal analysis

  Affiliation Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Barcelona. Barcelona, Spain

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• Enric Jo ,

  Roles Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Reig Jofre Group. Sant Joan Despí, Spain

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• Montserrat Miñarro ,

  Roles Formal analysis

  ¶‡ These authors also contributed equally to this work.

  Affiliation Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Barcelona. Barcelona, Spain

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• Albert Manich ,

  Contributed equally to this work with: Paloma Flórez Borges, Encarna García-Montoya, Pilar Pérez-Lozano, Albert Manich

  Roles Data curation

  Affiliation IQAC-CSIC. Institute of Advanced Chemistry of Catalonia. Barcelona, Spain

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• Josep Maria Suñé-Negre

  Roles Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Barcelona. Barcelona, Spain

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