Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1α deacetylation

• Mijung Lee ,

  Contributed equally to this work with: Mijung Lee, Jae-Jun Ban

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – original draft

  Affiliation Department of Neurology, Seoul National University Hospital, Seoul, South Korea

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• Jae-Jun Ban ,

  Contributed equally to this work with: Mijung Lee, Jae-Jun Ban

  Roles Conceptualization, Data curation, Investigation, Methodology, Software, Validation, Writing – original draft

  Affiliation Department of Neurology, Seoul National University Hospital, Seoul, South Korea

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• Jin-Young Chung,

  Roles Investigation, Methodology, Resources, Visualization

  Affiliation Department of Veterinary Internal Medicine and Geriatrics, College of Veterinary Medicine, Kangwon National University, Gangwon, South Korea

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• Wooseok Im ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: imwooseok@gmail.com (WI); kimmanho@snu.ac.kr (MK)

  Affiliations Department of Neurology, Seoul National University Hospital, Seoul, South Korea, Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea

  http://orcid.org/0000-0002-0866-4405

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• Manho Kim

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: imwooseok@gmail.com (WI); kimmanho@snu.ac.kr (MK)

  Affiliations Department of Neurology, Seoul National University Hospital, Seoul, South Korea, Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea, Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul, South Korea

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