Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Jamie L. Wilson; Rod Warburton; Linda Taylor; Deniz Toksoz; Nicholas Hill; Peter Polgar

doi:10.1371/journal.pone.0195780

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Open Access

Peer-reviewed

Research Article

Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Jamie L. Wilson ,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – original draft, Writing – review & editing

* E-mail: jwilson8@tuftsmedicalcenter.org

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America

http://orcid.org/0000-0001-7464-646X

⨯
Rod Warburton,

Roles Methodology, Validation, Writing – review & editing

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America
⨯
Linda Taylor,

Roles Methodology, Writing – review & editing

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America
⨯
Deniz Toksoz,

Roles Writing – review & editing

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America
⨯
Nicholas Hill,

Roles Resources, Writing – review & editing

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America
⨯
Peter Polgar

Roles Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America
⨯

Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Jamie L. Wilson,
Rod Warburton,
Linda Taylor,
Deniz Toksoz,
Nicholas Hill,
Peter Polgar

Published: April 12, 2018
https://doi.org/10.1371/journal.pone.0195780

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