Discovery of genetic variants of the kinases that activate tenofovir among individuals in the United States, Thailand, and South Africa: HPTN067

• Dominique B. Figueroa ,

  Contributed equally to this work with: Dominique B. Figueroa, Joseph Tillotson

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Joseph Tillotson ,

  Contributed equally to this work with: Dominique B. Figueroa, Joseph Tillotson

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine (Division of Clinical Pharmacology), Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Maoji Li,

  Roles Data curation, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America

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• Estelle Piwowar-Manning,

  Roles Project administration, Writing – review & editing

  Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Craig W. Hendrix,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Medicine (Division of Clinical Pharmacology), Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Timothy H. Holtz,

  Roles Investigation, Writing – review & editing

  Affiliation HIV/STD Research Program, Thailand Ministry of Public Health–U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand. Division of HIV/AIDS Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• Kevin Bokoch,

  Roles Project administration, Writing – review & editing

  Affiliation FHI 360, Research Triangle Park, NC, United States of America

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• Linda-Gail Bekker,

  Roles Investigation, Writing – review & editing

  Affiliation The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa

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• Frits van Griensven,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Epidemiology and Biostatistics, University of California, San Francisco School of Medicine, San Francisco, CA, United States of America

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• Sharon Mannheimer,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Epidemiology and Department of Medicine, Columbia University Mailman School of Public Health, New York, NY, United States of America

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• James P. Hughes,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA, United States of America

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• Robert M. Grant,

  Roles Investigation, Writing – review & editing

  Affiliation Gladstone Institutes, University of California, San Francisco, San Francisco, CA, United States of America

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• Namandjé N. Bumpus

  Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nbumpus1@jhmi.edu

  Affiliation Department of Medicine (Division of Clinical Pharmacology), Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  http://orcid.org/0000-0002-6096-3824

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