Epidemiological links between tuberculosis cases identified twice as efficiently by whole genome sequencing than conventional molecular typing: A population-based study

Rana Jajou; Albert de Neeling; Rianne van Hunen; Gerard de Vries; Henrieke Schimmel; Arnout Mulder; Richard Anthony; Wim van der Hoek; Dick van Soolingen

doi:10.1371/journal.pone.0195413

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Open Access

Peer-reviewed

Research Article

Epidemiological links between tuberculosis cases identified twice as efficiently by whole genome sequencing than conventional molecular typing: A population-based study

Rana Jajou ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Visualization, Writing – original draft

* E-mail: rana.jajou@rivm.nl

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

http://orcid.org/0000-0001-5957-5261

⨯
Albert de Neeling,

Roles Software

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Rianne van Hunen,

Roles Data curation

Affiliations National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, KNCV Tuberculosis Foundation, The Hague, The Netherlands
⨯
Gerard de Vries,

Roles Writing – review & editing

Affiliations National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, KNCV Tuberculosis Foundation, The Hague, The Netherlands
⨯
Henrieke Schimmel,

Roles Data curation

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Arnout Mulder,

Roles Resources

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Richard Anthony,

Roles Visualization, Writing – review & editing

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Wim van der Hoek,

Roles Writing – review & editing

Affiliation National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Dick van Soolingen

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, Radboud University Medical Centre, Department of Medical Microbiology, Nijmegen, The Netherlands
⨯

Epidemiological links between tuberculosis cases identified twice as efficiently by whole genome sequencing than conventional molecular typing: A population-based study

Rana Jajou,
Albert de Neeling,
Rianne van Hunen,
Gerard de Vries,
Henrieke Schimmel,
Arnout Mulder,
Richard Anthony,
Wim van der Hoek,
Dick van Soolingen

Published: April 4, 2018
https://doi.org/10.1371/journal.pone.0195413

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Tuberculosis
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Genetic epidemiology
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Mycobacterium tuberculosis
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Genotyping
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Single nucleotide polymorphisms
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