Dissimilar flexibility of α and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors

• Gusztáv Schay ,

  Contributed equally to this work with: Gusztáv Schay, Judit Fidy, Levente Herenyi

  Roles Conceptualization, Formal analysis, Investigation, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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• András D. Kaposi ,

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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• László Smeller ,

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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• Krisztián Szigeti ,

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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• Judit Fidy ,

  Contributed equally to this work with: Gusztáv Schay, Judit Fidy, Levente Herenyi

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

  ⨯
• Levente Herenyi

  Contributed equally to this work with: Gusztáv Schay, Judit Fidy, Levente Herenyi

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: herenyi.levente@med.semmelweis-univ.hu

  Affiliation Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

  http://orcid.org/0000-0003-0535-0256

  ⨯