Low SOX2 expression marks a distinct subset of adenoid cystic carcinoma of the head and neck and is associated with an advanced tumor stage

• Julia Thierauf ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: JuliaCara.Thierauf@med.uni-heidelberg.de

  Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany

  http://orcid.org/0000-0002-9607-3866

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• Stephanie E. Weissinger,

  Roles Data curation, Resources

  Affiliation Institute of Pathology, University Medical Center Ulm, Ulm, Germany

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• Johannes A. Veit,

  Roles Writing – review & editing

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany

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• Annette Affolter,

  Roles Formal analysis, Methodology

  Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany

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• Natalia K. Laureano,

  Roles Formal analysis, Validation

  Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany, Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany, Department of Oral Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

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• Dirk Beutner,

  Roles Resources

  Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, Cologne, Germany, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Göttingen, Göttingen, Germany

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• Gregor Heiduschka,

  Roles Resources

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, Vienna General Hospital, Vienna, Austria

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• Lorenz Kadletz,

  Roles Resources

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, Vienna General Hospital, Vienna, Austria

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• Moritz Meyer,

  Roles Resources

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, Cologne, Germany

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• Alexander Quaas,

  Roles Data curation

  Affiliation Institute of Pathology, University Hospital Cologne, Cologne, Germany

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• Peter Plinkert,

  Roles Project administration, Supervision

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany

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• Thomas K. Hoffmann,

  Roles Conceptualization, Investigation

  Affiliation Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany

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• Jochen Hess

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany, Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany

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