MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells

Yu Cong; Brit J. Hart; Robin Gross; Huanying Zhou; Matthew Frieman; Laura Bollinger; Jiro Wada; Lisa E. Hensley; Peter B. Jahrling; Julie Dyall; Michael R. Holbrook

doi:10.1371/journal.pone.0194868

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Open Access

Peer-reviewed

Research Article

MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells

Yu Cong,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Brit J. Hart,

Roles Investigation

Current address: Naval Medical Research Center (NMRC), Frederick, Maryland, United States of America

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Robin Gross,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Huanying Zhou,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Matthew Frieman,

Roles Investigation, Resources

Affiliation Department of Microbiology and Immunology, The University of Maryland School of Medicine, Baltimore, MD, United States of America
⨯
Laura Bollinger,

Roles Writing – review & editing

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Jiro Wada,

Roles Visualization

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Lisa E. Hensley,

Roles Resources

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Peter B. Jahrling,

Roles Resources

Affiliations Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America, Emerging Viral Pathogen Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Julie Dyall,

Roles Data curation, Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America
⨯
Michael R. Holbrook

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

* E-mail: Michael.holbrook@nih.gov

Affiliation Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, Maryland, United States of America

http://orcid.org/0000-0002-0824-2667

⨯

MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells

Yu Cong,
Brit J. Hart,
Robin Gross,
Huanying Zhou,
Matthew Frieman,
Laura Bollinger,
Jiro Wada,
Lisa E. Hensley,
Peter B. Jahrling,
Julie Dyall

Published: March 22, 2018
https://doi.org/10.1371/journal.pone.0194868

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