Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro

Nadeschda Schmidt; Jennifer Schulze; Dawid P. Warwas; Nina Ehlert; Thomas Lenarz; Athanasia Warnecke; Peter Behrens

doi:10.1371/journal.pone.0194778

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Peer-reviewed

Research Article

Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro

Nadeschda Schmidt ,

Contributed equally to this work with: Nadeschda Schmidt, Jennifer Schulze

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Institut für Anorganische Chemie, Leibniz Universität Hannover, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany

http://orcid.org/0000-0002-6516-4562

⨯
Jennifer Schulze ,

Contributed equally to this work with: Nadeschda Schmidt, Jennifer Schulze

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany
⨯
Dawid P. Warwas,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Institut für Anorganische Chemie, Leibniz Universität Hannover, Hannover, Germany
⨯
Nina Ehlert,

Roles Investigation, Supervision, Writing – review & editing

Affiliations Institut für Anorganische Chemie, Leibniz Universität Hannover, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany
⨯
Thomas Lenarz,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany
⨯
Athanasia Warnecke,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliations Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany
⨯
Peter Behrens

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: Peter.Behrens@acb.uni-hannover.de

Affiliations Institut für Anorganische Chemie, Leibniz Universität Hannover, Hannover, Germany, Cluster of Excellence Hearing4all, Hannover, Germany
⨯

Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro

Nadeschda Schmidt,
Jennifer Schulze,
Dawid P. Warwas,
Nina Ehlert,
Thomas Lenarz,
Athanasia Warnecke,
Peter Behrens

Published: March 27, 2018
https://doi.org/10.1371/journal.pone.0194778

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