Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction

• Fang-Fei Wei ,

  Contributed equally to this work with: Fang-Fei Wei, Sander Trenson

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

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• Sander Trenson ,

  Contributed equally to this work with: Fang-Fei Wei, Sander Trenson

  Roles Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Cardiology, University Hospitals Leuven, Leuven, Belgium

  ⨯
• Pierre Monney,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Cardiology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland

  ⨯
• Wen-Yi Yang,

  Roles Data curation, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

  ⨯
• Menno Pruijm,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Nephrology, University Hospital of Lausanne, Lausanne, Switzerland

  ⨯
• Zhen-Yu Zhang,

  Roles Data curation, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

  ⨯
• Yassine Bouatou,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pathology, Academisch Medisch Centrum, Universiteit van Amsterdam, Amsterdam, The Netherlands

  ⨯
• Qi-Fang Huang,

  Roles Data curation, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

  ⨯
• Belen Ponte,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Nephrology, University Hospital of Geneva, Geneva, Switzerland

  ⨯
• Pierre-Yves Martin,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Nephrology, University Hospital of Geneva, Geneva, Switzerland

  ⨯
• Lutgarde Thijs,

  Roles Data curation, Formal analysis, Software, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

  ⨯
• Tatiana Kuznetsova,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

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• Karel Allegaert,

  Roles Supervision, Writing – review & editing

  Affiliations Research Unit Organ Systems, Department of Development and Regeneration, University of Leuven, Leuven, Belgium, Department of Pediatric Surgery, Erasmus Medical Center, Sophia Children’s Hospital, Rotterdam, The Netherlands

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• Stefan Janssens,

  Roles Supervision, Writing – review & editing

  Affiliation Division of Cardiology, University Hospitals Leuven, Leuven, Belgium

  ⨯
• Cees Vermeer,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliation R&D Group VitaK, Maastricht University, Maastricht, The Netherlands

  ⨯
• Peter Verhamme,

  Roles Supervision, Writing – review & editing

  Affiliation Research Unit Molecular and Vascular Biology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium

  ⨯
• Michel Burnier,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Nephrology, University Hospital of Lausanne, Lausanne, Switzerland

  ⨯
• Murielle Bochud,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Division of Chronic Disease, Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland

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• Georg Ehret,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Cardiology, University Hospital of Geneva, Geneva, Switzerland, Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, John Hopkins University, Baltimore, Maryland, United States of America

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•  [ ... ],
• Jan A. Staessen

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: jan.staessen@med.kuleuven.be

  Affiliations Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium, R&D Group VitaK, Maastricht University, Maastricht, The Netherlands

  http://orcid.org/0000-0002-3026-1637

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