Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children

Joy Benadiba; Marc Ansari; Maja Krajinovic; Marie-France Vachon; Michel Duval; Pierre Teira; Sonia Cellot; Henrique Bittencourt

doi:10.1371/journal.pone.0193862

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Open Access

Peer-reviewed

Research Article

Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children

Joy Benadiba ,

Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

* E-mail: benadiba.j@chu-nice.fr

Affiliation Department of Hemato-Oncology Pediatric, Nice University Hospital, Nice, France

http://orcid.org/0000-0003-4229-7749

⨯
Marc Ansari,

Roles Validation

Affiliations Department of Pediatrics, Geneva University Hospital, Geneva, Switzerland, Cansearch Research Laboratory, Geneva University Medical School, Geneva, Switzerland
⨯
Maja Krajinovic,

Roles Validation

Affiliations Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada, Clinical Pharmacology Unit, Ste-Justine Hospital, Montreal, Canada, Department of Pediatrics, Faculty of Medicine - University of Montreal, Montreal, Canada
⨯
Marie-France Vachon,

Roles Validation

Affiliation Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada
⨯
Michel Duval,

Roles Validation

Affiliations Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada, Department of Pediatrics, Faculty of Medicine - University of Montreal, Montreal, Canada
⨯
Pierre Teira,

Roles Validation

Affiliations Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada, Department of Pediatrics, Faculty of Medicine - University of Montreal, Montreal, Canada
⨯
Sonia Cellot,

Roles Validation

Affiliations Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada, Department of Pediatrics, Faculty of Medicine - University of Montreal, Montreal, Canada
⨯
Henrique Bittencourt

Roles Supervision, Validation, Writing – review & editing

Affiliations Hematology-Oncology Division - Centre de Cancérologie Charles-Bruneau, Ste-Justine Hospital, Montréal, Canada, Department of Pediatrics, Faculty of Medicine - University of Montreal, Montreal, Canada
⨯

Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children

Joy Benadiba,
Marc Ansari,
Maja Krajinovic,
Marie-France Vachon,
Michel Duval,
Pierre Teira,
Sonia Cellot,
Henrique Bittencourt

Published: April 2, 2018
https://doi.org/10.1371/journal.pone.0193862

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Hematopoietic stem cell transplantation
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Adjustment of dosage at steady state
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Acute myeloid leukemia
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