Serum cystatin C is an independent biomarker associated with the renal resistive index in patients with chronic kidney disease

Ayu Ogawa-Akiyama; Hitoshi Sugiyama; Masashi Kitagawa; Keiko Tanaka; Akifumi Onishi; Toshio Yamanari; Hiroshi Morinaga; Haruhito Adam Uchida; Kazufumi Nakamura; Hiroshi Ito; Jun Wada

doi:10.1371/journal.pone.0193695

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Open Access

Peer-reviewed

Research Article

Serum cystatin C is an independent biomarker associated with the renal resistive index in patients with chronic kidney disease

Ayu Ogawa-Akiyama,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Hitoshi Sugiyama ,

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

* E-mail: hitoshis@md.okayama-u.ac.jp

Affiliations Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Department of Human Resource Development of Dialysis Therapy for Kidney Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

http://orcid.org/0000-0002-4127-6471

⨯
Masashi Kitagawa,

Roles Conceptualization, Validation

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Keiko Tanaka,

Roles Data curation

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Akifumi Onishi,

Roles Data curation, Validation

Affiliations Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Department of Human Resource Development of Dialysis Therapy for Kidney Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Toshio Yamanari,

Roles Data curation

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Hiroshi Morinaga,

Roles Formal analysis

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Haruhito Adam Uchida,

Roles Methodology, Validation

Affiliations Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Kazufumi Nakamura,

Roles Methodology, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Hiroshi Ito,

Roles Methodology, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Jun Wada

Roles Supervision, Writing – review & editing

Affiliation Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯

Serum cystatin C is an independent biomarker associated with the renal resistive index in patients with chronic kidney disease

Ayu Ogawa-Akiyama,
Hitoshi Sugiyama,
Masashi Kitagawa,
Keiko Tanaka,
Akifumi Onishi,
Toshio Yamanari,
Hiroshi Morinaga,
Haruhito Adam Uchida,
Kazufumi Nakamura,
Hiroshi Ito

Published: March 7, 2018
https://doi.org/10.1371/journal.pone.0193695

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Chronic kidney disease
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Blood pressure
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Renal system
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Glomerular filtration rate
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