Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9

• Kazuhisa Honma,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Tottori, Japan

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• Satoshi Abe,

  Roles Data curation, Formal analysis, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliation Chromosome Engineering Research Center, Tottori University, Yonago, Tottori, Japan

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• Takeshi Endo,

  Roles Methodology, Writing – review & editing

  Affiliation Tottori Industrial Promotion Organization, Tottori, Tottori, Japan

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• Narumi Uno,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Tottori, Japan, Chromosome Engineering Research Center, Tottori University, Yonago, Tottori, Japan

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• Mitsuo Oshimura,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Chromosome Engineering Research Center, Tottori University, Yonago, Tottori, Japan

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• Tetsuya Ohbayashi,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Division of Laboratory Animal Science, Research Center for Bioscience and Technology, Tottori University, Yonago, Tottori, Japan

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• Yasuhiro Kazuki

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: kazuki@grape.med.tottori-u.ac.jp

  Affiliations Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Tottori, Japan, Chromosome Engineering Research Center, Tottori University, Yonago, Tottori, Japan

  http://orcid.org/0000-0003-4818-4710

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