Whole genome bisulfite sequencing reveals unique adaptations to high-altitude environments in Tibetan chickens

Zengrong Zhang; Huarui Du; Lijun Bai; Chaowu Yang; Qingyun Li; Xiaocheng Li; Mohan Qiu; Chunlin Yu; Zongrong Jiang; Xiaoyu Jiang; Lan Liu; Chenming Hu; Bo Xia; Xia Xiong; Xiaoyan Song; Xiaosong Jiang

doi:10.1371/journal.pone.0193597

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Open Access

Peer-reviewed

Research Article

Whole genome bisulfite sequencing reveals unique adaptations to high-altitude environments in Tibetan chickens

Zengrong Zhang,

Roles Methodology, Writing – original draft

Affiliations Sichuan Animal Science Academy, Chengdu, Sichuan, China, Animal Breeding and Genetics key Laboratory of Sichuan Province, Chengdu, Sichuan, China
⨯
Huarui Du,

Roles Data curation, Formal analysis

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Lijun Bai,

Roles Investigation, Methodology

Affiliation BGI-Shenzhen, Shenzhen, China
⨯
Chaowu Yang,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Qingyun Li,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Xiaocheng Li,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Mohan Qiu,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Chunlin Yu,

Roles Investigation

Affiliation Animal Breeding and Genetics key Laboratory of Sichuan Province, Chengdu, Sichuan, China
⨯
Zongrong Jiang,

Roles Investigation

Affiliation Ganzi Animal Science institute, Ganzi Tibetan Autonomous Prefecture, Kangding, Sichuan, China
⨯
Xiaoyu Jiang,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Lan Liu,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Chenming Hu,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Bo Xia,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Xia Xiong,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
Xiaoyan Song,

Roles Investigation

Affiliation Sichuan Animal Science Academy, Chengdu, Sichuan, China
⨯
[ ... ],
Xiaosong Jiang

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

* E-mail: xsjiang2017@163.com.

Affiliations Sichuan Animal Science Academy, Chengdu, Sichuan, China, Animal Breeding and Genetics key Laboratory of Sichuan Province, Chengdu, Sichuan, China

http://orcid.org/0000-0002-7114-869X

⨯
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Whole genome bisulfite sequencing reveals unique adaptations to high-altitude environments in Tibetan chickens

Zengrong Zhang,
Huarui Du,
Lijun Bai,
Chaowu Yang,
Qingyun Li,
Xiaocheng Li,
Mohan Qiu,
Chunlin Yu,
Zongrong Jiang,
Xiaoyu Jiang

Published: March 21, 2018
https://doi.org/10.1371/journal.pone.0193597

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DNA methylation
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Chickens
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Tibetan people
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Genome sequencing
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