Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016

• Arif Khan ,

  Roles Conceptualization, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: akhan@nwcrc.net

  Affiliations Northwest Clinical Research Center, Bellevue, Washington, United States of America, Department of Psychiatry, Duke University School of Medicine, Durham, North Carolina, United States of America

  http://orcid.org/0000-0001-9510-6083

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• Kaysee Fahl Mar,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Northwest Clinical Research Center, Bellevue, Washington, United States of America

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• Joshua Schilling,

  Roles Supervision, Validation, Writing – review & editing

  Affiliation Department of Cardiology, Baystate Medical Center, University of Massachusetts, Springfield, Massachusetts, United States of America

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• Walter A. Brown

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, United States of America

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