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Open Access
Peer-reviewed
Research Article
Low apolipoprotein A-I levels in Friedreich’s ataxia and in frataxin-deficient cells: Implications for therapy
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QingQing Wang,
Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Penn SRP Center and Center of Excellence in Environmental Toxicology Center, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, Pennsylvania, United States of America
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Lili Guo,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Penn SRP Center and Center of Excellence in Environmental Toxicology Center, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, Pennsylvania, United States of America
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Cassandra J. Strawser,
Roles Data curation, Investigation, Project administration, Writing – review & editing
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Neurology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Lauren A. Hauser,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Neurology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Wei-Ting Hwang,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliation Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Nathaniel W. Snyder,
Roles Formal analysis, Funding acquisition, Investigation, Writing – review & editing
Affiliation AJ Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania, United States of America
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David R. Lynch,
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Neurology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Clementina Mesaros,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Penn SRP Center and Center of Excellence in Environmental Toxicology Center, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, Pennsylvania, United States of America
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Ian A. Blair
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: ianblair@upenn.edu
Affiliations Penn/CHOP Center of Excellence in Friedreich’s Ataxia, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Penn SRP Center and Center of Excellence in Environmental Toxicology Center, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, Pennsylvania, United States of America
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Low apolipoprotein A-I levels in Friedreich’s ataxia and in frataxin-deficient cells: Implications for therapy
- QingQing Wang,
- Lili Guo,
- Cassandra J. Strawser,
- Lauren A. Hauser,
- Wei-Ting Hwang,
- Nathaniel W. Snyder,
- David R. Lynch,
- Clementina Mesaros,
- Ian A. Blair
- Published: February 15, 2018
- https://doi.org/10.1371/journal.pone.0192779