Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas

• Verena Sailer ,

  Contributed equally to this work with: Verena Sailer, Arthur Charpentier

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliations Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, United States of America, Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, United States of America

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• Arthur Charpentier ,

  Contributed equally to this work with: Verena Sailer, Arthur Charpentier

  Roles Data curation, Formal analysis

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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• Joern Dietrich,

  Roles Data curation, Formal analysis, Software

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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• Timo J. Vogt,

  Roles Formal analysis, Writing – review & editing

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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• Alina Franzen,

  Roles Formal analysis, Writing – review & editing

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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• Friedrich Bootz,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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• Dimo Dietrich ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: dimo.dietrich@gmail.com

  ¶‡ These authors contributed equally as joint senior authors of this work.

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

  http://orcid.org/0000-0001-9794-7927

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• Andreas Schroeck

  Roles Writing – review & editing

  ¶‡ These authors contributed equally as joint senior authors of this work.

  Affiliation University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany

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