Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy

• Ann-Kathrin Ernst ,

  Contributed equally to this work with: Ann-Kathrin Ernst, Annika Putscher

  Roles Data curation, Investigation

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Annika Putscher ,

  Contributed equally to this work with: Ann-Kathrin Ernst, Annika Putscher

  Roles Data curation, Investigation

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Timur R. Samatov,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliations SRC Bioclinicum, Moscow, Russia, Moscow State University of Mechanical Engineering, Moscow, Russia

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• Anna Suling,

  Roles Formal analysis, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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• Vladimir V. Galatenko,

  Roles Formal analysis, Methodology, Software, Validation, Writing – review & editing

  Affiliations SRC Bioclinicum, Moscow, Russia, Moscow State University, Moscow, Russia, National Research University Higher School of Economics, Moscow, Russia

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• Maxim Yu Shkurnikov,

  Roles Formal analysis, Methodology, Software

  Affiliation SRC Bioclinicum, Moscow, Russia

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• Evgeny N. Knyazev,

  Roles Formal analysis, Methodology, Software, Validation, Writing – review & editing

  Affiliation SRC Bioclinicum, Moscow, Russia

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• Alexander G. Tonevitsky,

  Roles Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliations Moscow State University, Moscow, Russia, Department of Translational Oncology, National Center of Medical Radiological Research, Obninsk, Russia

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• Thomas Haalck,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Outpatient Center, Department of Dermatology, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Tobias Lange,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Hanna Maar,

  Roles Data curation, Investigation, Validation

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Jennifer Schröder- Schwarz,

  Roles Data curation, Investigation, Validation

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Kristoffer Riecken,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany

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• Udo Schumacher,

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

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• Daniel Wicklein

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: d.wicklein@uke.de

  Affiliation Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany

  http://orcid.org/0000-0003-0007-8708

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