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Open Access
Peer-reviewed
Research Article
Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells
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Weikai Zhang ,
Contributed equally to this work with: Weikai Zhang, Zhitao Li
Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing
Affiliations Medical College, Henan University of Science and Technology, Luoyang, P. R. China, Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, P. R. China, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Zhitao Li ,
Contributed equally to this work with: Weikai Zhang, Zhitao Li
Roles Methodology, Supervision
Affiliation Medical College, Henan University of Science and Technology, Luoyang, P. R. China
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Zihua Wang,
Roles Data curation
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Chunyan Yue,
Roles Data curation
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Hui Zheng,
Roles Software
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Ren Li,
Roles Software
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Mingxing Zhou,
Roles Software
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Zhiyuan Hu ,
Roles Project administration, Supervision, Writing – review & editing
* E-mail: weizw@nanoctr.cn (ZW); huzy@nanoctr.cn (ZH); liqin@bit.edu.cn (QL)
Affiliations CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China, Sino-Danish College, University of Chinese Academy of Sciences, Beijing, P. R. China, Yangtze River Delta Academy of Nanotechnology and Industry Development Research, Jiaxing, Zhejiang Province, P. R. China
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Zewen Wei ,
Roles Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: weizw@nanoctr.cn (ZW); huzy@nanoctr.cn (ZH); liqin@bit.edu.cn (QL)
Affiliation CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, P. R. China
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Qin Li
Roles Software, Supervision
* E-mail: weizw@nanoctr.cn (ZW); huzy@nanoctr.cn (ZH); liqin@bit.edu.cn (QL)
Affiliation Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, P. R. China
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Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells
- Weikai Zhang,
- Zhitao Li,
- Zihua Wang,
- Chunyan Yue,
- Hui Zheng,
- Ren Li,
- Mingxing Zhou,
- Zhiyuan Hu,
- Zewen Wei,
- Qin Li
- Published: February 9, 2018
- https://doi.org/10.1371/journal.pone.0192506