The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity

Igor Sabljić; Marko Tomin; Mihaela Matovina; Iva Sučec; Ana Tomašić Paić; Antonija Tomić; Marija Abramić; Sanja Tomić

doi:10.1371/journal.pone.0192488

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Peer-reviewed

Research Article

The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity

Igor Sabljić ,

Contributed equally to this work with: Igor Sabljić, Marko Tomin

Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Marko Tomin ,

Contributed equally to this work with: Igor Sabljić, Marko Tomin

Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia

http://orcid.org/0000-0001-6894-6810

⨯
Mihaela Matovina,

Roles Formal analysis, Investigation, Supervision, Validation, Writing – review & editing

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Iva Sučec,

Roles Formal analysis, Investigation

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Ana Tomašić Paić,

Roles Formal analysis, Investigation

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Antonija Tomić,

Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – review & editing

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Marija Abramić,

Roles Conceptualization, Resources, Writing – original draft

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia
⨯
Sanja Tomić

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: sanja.tomic@irb.hr

Affiliation Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia

http://orcid.org/0000-0002-0550-0878

⨯

The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity

Igor Sabljić,
Marko Tomin,
Mihaela Matovina,
Iva Sučec,
Ana Tomašić Paić,
Antonija Tomić,
Marija Abramić,
Sanja Tomić

Published: February 8, 2018
https://doi.org/10.1371/journal.pone.0192488

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