A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual

Joydeep Sarkar; Gaurav Dwivedi; Qian Chen; Iris E. Sheu; Mark Paich; Colleen M. Chelini; Paul M. D'Alessandro; Samuel P. Burns

doi:10.1371/journal.pone.0192472

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Open Access

Peer-reviewed

Research Article

A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual

Joydeep Sarkar,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Writing – review & editing

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Gaurav Dwivedi,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Qian Chen,

Roles Data curation, Formal analysis, Investigation, Project administration, Software, Validation, Visualization, Writing – review & editing

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Iris E. Sheu,

Roles Data curation, Investigation, Software

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Mark Paich,

Roles Conceptualization, Investigation, Methodology, Supervision

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Colleen M. Chelini,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Paul M. D'Alessandro,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America
⨯
Samuel P. Burns

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

* E-mail: samuel.p.burns@pwc.com

Affiliation PricewaterhouseCoopers LLP, New York, New York, United States of America

http://orcid.org/0000-0002-0861-327X

⨯

A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual

Joydeep Sarkar,
Gaurav Dwivedi,
Qian Chen,
Iris E. Sheu,
Mark Paich,
Colleen M. Chelini,
Paul M. D'Alessandro,
Samuel P. Burns

Published: February 14, 2018
https://doi.org/10.1371/journal.pone.0192472

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Insulin
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Glucose
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Diabetes mellitus
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