Efficacy and safety of Modified Tongxie Yaofang in diarrhea-predominant irritable bowel syndrome management: A meta-analysis of randomized, positive medicine-controlled trials

Yun-kai Dai; Dan-yan Li; Yun-zhan Zhang; Meng-xin Huang; Yi-le Zhou; Jin-tong Ye; Qi Wang; Ling Hu

doi:10.1371/journal.pone.0192319

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Open Access

Peer-reviewed

Research Article

Efficacy and safety of Modified Tongxie Yaofang in diarrhea-predominant irritable bowel syndrome management: A meta-analysis of randomized, positive medicine-controlled trials

Yun-kai Dai ,

Contributed equally to this work with: Yun-kai Dai, Dan-yan Li

Roles Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Dan-yan Li ,

Contributed equally to this work with: Yun-kai Dai, Dan-yan Li

Roles Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Yun-zhan Zhang,

Roles Data curation, Investigation, Methodology, Software

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Meng-xin Huang,

Roles Methodology, Software

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Yi-le Zhou,

Roles Methodology, Software

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Jin-tong Ye,

Roles Methodology, Software

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Qi Wang ,

Roles Project administration, Supervision, Visualization

* E-mail: drhuling@163.com(LH); wqitcm@qq.com(QW)

Affiliation Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Ling Hu

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Validation, Visualization

* E-mail: drhuling@163.com(LH); wqitcm@qq.com(QW)

Affiliation Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China

http://orcid.org/0000-0003-3104-8050

⨯

Efficacy and safety of Modified Tongxie Yaofang in diarrhea-predominant irritable bowel syndrome management: A meta-analysis of randomized, positive medicine-controlled trials

Yun-kai Dai,
Dan-yan Li,
Yun-zhan Zhang,
Meng-xin Huang,
Yi-le Zhou,
Jin-tong Ye,
Qi Wang,
Ling Hu

Published: February 6, 2018
https://doi.org/10.1371/journal.pone.0192319

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Irritable bowel syndrome
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Metaanalysis
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Abdominal pain
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Diarrhea
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Adverse events
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Colon
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Defecation
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Randomized controlled trials
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