MR-guided transcranial focused ultrasound safely enhances interstitial dispersion of large polymeric nanoparticles in the living brain

• David S. Hersh ,

  Contributed equally to this work with: David S. Hersh, Pavlos Anastasiadis

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Pavlos Anastasiadis ,

  Contributed equally to this work with: David S. Hersh, Pavlos Anastasiadis

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Ali Mohammadabadi,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Ben A. Nguyen,

  Roles Data curation, Formal analysis, Methodology, Software

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Sijia Guo,

  Roles Formal analysis, Methodology, Software

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Jeffrey A. Winkles,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliations Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Anthony J. Kim,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Rao Gullapalli,

  Roles Formal analysis, Investigation, Methodology, Software, Supervision, Writing – review & editing

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Asaf Keller,

  Roles Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Victor Frenkel ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: VFrenkel@som.umaryland.edu (VF); GWoodworth@som.umaryland.edu (GFW)

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Graeme F. Woodworth

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: VFrenkel@som.umaryland.edu (VF); GWoodworth@som.umaryland.edu (GFW)

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  http://orcid.org/0000-0001-9663-0768

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