Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations

• Anusha Jayaraman ,

  Contributed equally to this work with: Anusha Jayaraman, Praveen Kumar

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Beaumont Health System, Beaumont Research Institute, Royal Oak, Michigan, United States of America

  Affiliation Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain

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• Praveen Kumar ,

  Contributed equally to this work with: Anusha Jayaraman, Praveen Kumar

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Current address: Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America

  Affiliation Beaumont Health System, Beaumont Research Institute, Royal Oak, Michigan, United States of America

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• Silvia Marin,

  Roles Conceptualization, Formal analysis, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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• Pedro de Atauri,

  Roles Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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• Francesca Mateo,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Cell Biology, Molecular Biology Institute of Barcelona, National Research Council (IBMB-CSIC), Barcelona, Spain

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• Timothy M. Thomson,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain, Department of Cell Biology, Molecular Biology Institute of Barcelona, National Research Council (IBMB-CSIC), Barcelona, Spain

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• Josep J. Centelles,

  Roles Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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• Stewart F. Graham,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Beaumont Health System, Beaumont Research Institute, Royal Oak, Michigan, United States of America

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• Marta Cascante

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: martacascante@ub.edu

  Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

  http://orcid.org/0000-0002-2062-4633

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