Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release

• Nils Wagner,

  Roles Conceptualization, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

  http://orcid.org/0000-0003-3318-251X

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• Scott Dieteren,

  Roles Investigation

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Niklas Franz,

  Roles Investigation

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Kernt Köhler,

  Roles Investigation, Validation

  Affiliation Institute of Veterinary Pathology, Justus Liebig University Giessen, Giessen, Germany

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• Katharina Mörs,

  Roles Visualization

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Luka Nicin,

  Roles Investigation

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Julia Schmidt,

  Roles Investigation

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Mario Perl,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision

  Affiliation BG-Trauma Center Murnau, Murnau, Germany

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• Ingo Marzi,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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• Borna Relja

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: info@bornarelja.com

  Affiliation Department of Trauma Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany

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