Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test

Dana Huskens; Yaqiu Sang; Joke Konings; Lisa van der Vorm; Bas de Laat; Hilde Kelchtermans; Mark Roest

doi:10.1371/journal.pone.0192079

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Open Access

Peer-reviewed

Research Article

Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test

Dana Huskens ,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: D.Huskens@thrombin.com

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands

http://orcid.org/0000-0002-5999-5685

⨯
Yaqiu Sang,

Roles Investigation, Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands
⨯
Joke Konings,

Roles Investigation, Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands
⨯
Lisa van der Vorm,

Roles Investigation, Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands, Department of Clinical Chemistry and Hematology, Gelre Hospitals, Apeldoorn, The Netherlands
⨯
Bas de Laat,

Roles Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands
⨯
Hilde Kelchtermans,

Roles Project administration, Resources, Supervision, Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands
⨯
Mark Roest

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands, Synapse Research Institute, Maastricht, the Netherlands
⨯

Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test

Dana Huskens,
Yaqiu Sang,
Joke Konings,
Lisa van der Vorm,
Bas de Laat,
Hilde Kelchtermans,
Mark Roest

Published: February 1, 2018
https://doi.org/10.1371/journal.pone.0192079

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Platelets
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Platelet activation
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Blood
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Flow cytometry
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