CD73-A2a adenosine receptor axis promotes innate B cell antibody responses to pneumococcal polysaccharide vaccination

David Allard; Roxanne Charlebois; Loise Gilbert; John Stagg; Pavel Chrobak

doi:10.1371/journal.pone.0191973

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Open Access

Peer-reviewed

Research Article

CD73-A2a adenosine receptor axis promotes innate B cell antibody responses to pneumococcal polysaccharide vaccination

David Allard,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Centre de Recherche du Centre Hospitalier l’Université de Montréal (CRCHUM), Faculté de Pharmacie de l’Université de Montréal et Institut du Cancer de Montréal, Montréal, Quebec, Canada
⨯
Roxanne Charlebois,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Centre de Recherche du Centre Hospitalier l’Université de Montréal (CRCHUM), Faculté de Pharmacie de l’Université de Montréal et Institut du Cancer de Montréal, Montréal, Quebec, Canada
⨯
Loise Gilbert,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Centre de Recherche du Centre Hospitalier l’Université de Montréal (CRCHUM), Faculté de Pharmacie de l’Université de Montréal et Institut du Cancer de Montréal, Montréal, Quebec, Canada
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John Stagg ,

Contributed equally to this work with: John Stagg, Pavel Chrobak

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: pavel.chrobak@hotmail.com (PC); john.stagg@umontreal.ca (JS)

Affiliation Centre de Recherche du Centre Hospitalier l’Université de Montréal (CRCHUM), Faculté de Pharmacie de l’Université de Montréal et Institut du Cancer de Montréal, Montréal, Quebec, Canada
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Pavel Chrobak

Contributed equally to this work with: John Stagg, Pavel Chrobak

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pavel.chrobak@hotmail.com (PC); john.stagg@umontreal.ca (JS)

Affiliation Centre de Recherche du Centre Hospitalier l’Université de Montréal (CRCHUM), Faculté de Pharmacie de l’Université de Montréal et Institut du Cancer de Montréal, Montréal, Quebec, Canada

http://orcid.org/0000-0003-3376-953X

⨯

CD73-A2a adenosine receptor axis promotes innate B cell antibody responses to pneumococcal polysaccharide vaccination

David Allard,
Roxanne Charlebois,
Loise Gilbert,
John Stagg,
Pavel Chrobak

Published: January 29, 2018
https://doi.org/10.1371/journal.pone.0191973

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B cells
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Vaccination and immunization
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Pneumococcus
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Adenosine
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Antibodies
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Antibody response
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