Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy

• José A. del Campo ,

  Contributed equally to this work with: José A. del Campo, Marta García-Valdecasas

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jantonio.delcampo@ciberehd.org

  Affiliation Department of Digestive Diseases and CIBERehd, Valme University Hospital, Servicio Andaluz de Salud, Seville, Spain

  http://orcid.org/0000-0002-6037-1028

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• Marta García-Valdecasas ,

  Contributed equally to this work with: José A. del Campo, Marta García-Valdecasas

  Roles Data curation, Methodology

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Antonio Gil-Gómez,

  Roles Methodology

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Ángela Rojas,

  Roles Methodology

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Paloma Gallego,

  Roles Methodology

  Affiliation Department of Digestive Diseases and CIBERehd, Valme University Hospital, Servicio Andaluz de Salud, Seville, Spain

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• Javier Ampuero,

  Roles Investigation

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Rocío Gallego-Durán,

  Roles Methodology

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Helena Pastor,

  Roles Methodology

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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• Lourdes Grande,

  Roles Investigation

  Affiliation Department of Digestive Diseases and CIBERehd, Valme University Hospital, Servicio Andaluz de Salud, Seville, Spain

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• Francisco J. Padillo,

  Roles Investigation, Methodology

  Affiliation Department of General Surgery, Rocío University Hospital, CSIC and University of Seville, Seville, Spain

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• Jordi Muntané,

  Roles Investigation, Methodology

  Affiliation Department of General Surgery, Rocío University Hospital, CSIC and University of Seville, Seville, Spain

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• Manuel Romero-Gómez

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Digestive Disease, Biomedicine Institute of Seville & CIBERehd, Rocío University Hospital, Seville, Spain

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