The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells

Maria Winzi; Nuria Casas Vila; Maciej Paszkowski-Rogacz; Li Ding; Svenja Noack; Mirko Theis; Falk Butter; Frank Buchholz

doi:10.1371/journal.pone.0191682

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Open Access

Peer-reviewed

Research Article

The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells

Maria Winzi,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Current address: Cellular Machines, BioTEC, Dresden University of Technology, Dresden, Germany

Affiliation Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany

http://orcid.org/0000-0003-4925-5605

⨯
Nuria Casas Vila,

Roles Investigation

Affiliation Quantitative Proteomics, Institute of Molecular Biology (IMB) gGmbH, Mainz, Germany
⨯
Maciej Paszkowski-Rogacz,

Roles Formal analysis

Affiliation Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany
⨯
Li Ding,

Roles Investigation, Resources

Affiliation Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany
⨯
Svenja Noack,

Roles Investigation

Affiliation Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany
⨯
Mirko Theis,

Roles Resources

Affiliation Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany
⨯
Falk Butter,

Roles Resources

Affiliation Quantitative Proteomics, Institute of Molecular Biology (IMB) gGmbH, Mainz, Germany
⨯
Frank Buchholz

Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing

* E-mail: frank.buchholz@tu-dresden.de

Affiliations Medical Systems Biology, Faculty of Medicine Carl Gustav Carus, University Cancer Center, TU Dresden, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, German Cancer Research Center (DKFZ), Heidelberg and German Cancer Consortium (DKTK) partner site Dresden, Dresden, Germany, National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany
⨯

The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells

Maria Winzi,
Nuria Casas Vila,
Maciej Paszkowski-Rogacz,
Li Ding,
Svenja Noack,
Mirko Theis,
Falk Butter,
Frank Buchholz

Published: January 24, 2018
https://doi.org/10.1371/journal.pone.0191682

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Cell differentiation
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Long non-coding RNA
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Wnt signaling cascade
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Pluripotency
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Hyperexpression techniques
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Transfection
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Messenger RNA
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Gene expression
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