Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads

Maryann C. Gruda; Karl-Gustav Ruggeberg; Pamela O’Sullivan; Tamaz Guliashvili; Andrew R. Scheirer; Thomas D. Golobish; Vincent J. Capponi; Phillip P. Chan

doi:10.1371/journal.pone.0191676

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Open Access

Peer-reviewed

Research Article

Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb^® sorbent porous polymer beads

Maryann C. Gruda ,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: mgruda@cytosorbents.com

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America

http://orcid.org/0000-0002-0724-3369

⨯
Karl-Gustav Ruggeberg,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Pamela O’Sullivan,

Roles Investigation, Methodology, Writing – original draft

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Tamaz Guliashvili,

Roles Investigation, Methodology, Writing – original draft

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Andrew R. Scheirer,

Roles Investigation, Methodology, Writing – original draft

Current address: Ethicon US, LLC, Somerville, New Jersey, United States of America

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Thomas D. Golobish,

Roles Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Vincent J. Capponi,

Roles Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯
Phillip P. Chan

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

Affiliation CytoSorbents Corporation, Monmouth Junction, New Jersey, United States of America
⨯

Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb^® sorbent porous polymer beads

Maryann C. Gruda,
Karl-Gustav Ruggeberg,
Pamela O’Sullivan,
Tamaz Guliashvili,
Andrew R. Scheirer,
Thomas D. Golobish,
Vincent J. Capponi,
Phillip P. Chan

Published: January 25, 2018
https://doi.org/10.1371/journal.pone.0191676

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