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Open Access
Peer-reviewed
Research Article
An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells
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Katharina Schrade ,
Contributed equally to this work with: Katharina Schrade, Jessica Tröger, Adeeb Eldahshan
Roles Investigation, Methodology
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Jessica Tröger ,
Contributed equally to this work with: Katharina Schrade, Jessica Tröger, Adeeb Eldahshan
Roles Investigation, Methodology
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Adeeb Eldahshan ,
Contributed equally to this work with: Katharina Schrade, Jessica Tröger, Adeeb Eldahshan
Roles Investigation, Methodology
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Kerstin Zühlke,
Roles Investigation, Methodology
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Kamal R. Abdul Azeez,
Roles Conceptualization, Investigation
Affiliation Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom
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Jonathan M. Elkins,
Roles Conceptualization, Investigation, Writing – review & editing
Affiliation Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom
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Martin Neuenschwander,
Roles Investigation
Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany
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Andreas Oder,
Roles Investigation
Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany
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Mohamed Elkewedi,
Roles Investigation, Methodology, Writing – original draft
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Sarah Jaksch,
Roles Investigation, Methodology
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
⨯ - Karsten Andrae,
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Jinliang Li,
Roles Investigation
Affiliation University of Miami Miller School of Medicine, Miami, United States of America
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Joao Fernandes,
Roles Investigation
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Paul Markus Müller,
Roles Investigation
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Stephan Grunwald,
Roles Investigation
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Stephen F. Marino,
Roles Investigation
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
⨯ -
Tanja Vukićević,
Roles Investigation
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Jenny Eichhorst,
Roles Investigation
Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany
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Burkhard Wiesner,
Roles Conceptualization, Data curation, Formal analysis, Methodology
Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany
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Marcus Weber,
Roles Conceptualization, Writing – review & editing
Affiliation Zuse Institute Berlin (ZIB), Germany
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Michael Kapiloff,
Roles Conceptualization, Writing – review & editing
Affiliation University of Miami Miller School of Medicine, Miami, United States of America
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Oliver Rocks,
Roles Writing – review & editing
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Oliver Daumke,
Roles Conceptualization, Writing – review & editing
Affiliation Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany
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Thomas Wieland,
Roles Conceptualization, Data curation, Writing – review & editing
Affiliations Institute of Experimental Pharmacology and Toxicology, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Germany
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Stefan Knapp,
Roles Conceptualization, Writing – review & editing
Affiliations Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom, Institute for Pharmaceutical Chemistry and Buchmann Institute, Goethe University, Frankfurt, Germany, DKTK (German Cancer Center Network), partner site Frankfurt/Main, Germany
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Jens Peter von Kries,
Roles Conceptualization, Data curation, Writing – review & editing
Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany
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Enno Klussmann
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft
* E-mail: enno.klussmann@mdc-berlin.de
Affiliations Max Delbrück Center for Molecular Medicine Berlin (MDC), Berlin, Germany, DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany
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An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells
- Katharina Schrade,
- Jessica Tröger,
- Adeeb Eldahshan,
- Kerstin Zühlke,
- Kamal R. Abdul Azeez,
- Jonathan M. Elkins,
- Martin Neuenschwander,
- Andreas Oder,
- Mohamed Elkewedi,
- Sarah Jaksch
- Published: January 26, 2018
- https://doi.org/10.1371/journal.pone.0191423