Combination COX-2 inhibitor and metformin attenuate rate of joint replacement in osteoarthritis with diabetes: A nationwide, retrospective, matched-cohort study in Taiwan

• Chieh-Hua Lu,

  Roles Writing – original draft

  Affiliations Department of Internal Medicine, Division of Endocrinology and Metabolism, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Medical Research, National Defense Medical Center, Taipei, Taiwan, ROC

  http://orcid.org/0000-0002-2179-9486

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• Chi-Hsiang Chung,

  Roles Formal analysis

  Affiliations School of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC, Taiwanese Injury Prevention and Safety Promotion Association, Taipei, Taiwan, ROC

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• Chien-Hsing Lee,

  Roles Conceptualization

  Affiliation Department of Internal Medicine, Division of Endocrinology and Metabolism, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC

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• Chang-Hsun Hsieh,

  Roles Conceptualization

  Affiliation Department of Internal Medicine, Division of Endocrinology and Metabolism, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC

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• Yi-Jen Hung,

  Roles Conceptualization

  Affiliation Department of Internal Medicine, Division of Endocrinology and Metabolism, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC

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• Fu-Huang Lin,

  Roles Conceptualization

  Affiliation School of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC

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• Chang-Huei Tsao,

  Roles Conceptualization

  Affiliations Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Microbiology & Immunology, National Defense Medical Center, Taipei, Taiwan, ROC

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• Po-Shiuan Hsieh ,

  Roles Writing – review & editing

  * E-mail: pshsieh@hotmail.com (PSH); chienwu@mail.ndmctsgh.edu.tw (WCC)

  Affiliations Department of Medical Research, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, ROC, Institute of Preventive Medicine, National Defense Medical Center, Taipei, Taiwan, ROC

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• Wu-Chien Chien

  Roles Writing – review & editing

  * E-mail: pshsieh@hotmail.com (PSH); chienwu@mail.ndmctsgh.edu.tw (WCC)

  Affiliations Department of Medical Research, National Defense Medical Center, Taipei, Taiwan, ROC, School of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC

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