Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk – Results from the PROG-IMT collaboration

• Matthias W. Lorenz ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft

  * E-mail: matthias.lorenz@em.uni-frankfurt.de

  Affiliation Department of Neurology, Goethe University, Frankfurt am Main, Germany

  http://orcid.org/0000-0002-7565-1751

  ⨯
• Lu Gao,

  Roles Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, United Kingdom

  ⨯
• Kathrin Ziegelbauer,

  Roles Data curation, Funding acquisition, Methodology, Project administration, Software, Writing – review & editing

  Affiliation Department of Neurology, Goethe University, Frankfurt am Main, Germany

  ⨯
• Giuseppe Danilo Norata,

  Roles Data curation, Validation, Writing – review & editing

  Affiliations Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy, SISA Center for the Study of Atherosclerosis, Bassini Hospital, Cinisello Balsamo, Italy

  ⨯
• Jean Philippe Empana,

  Roles Data curation, Methodology, Validation, Writing – review & editing

  Affiliation Paris Cardiovascular Research Centre (PARCC), University Paris Descartes, Sorbonne Paris Cité, UMR, Paris, France

  ⨯
• Irene Schmidtmann,

  Roles Data curation, Formal analysis, Validation

  Affiliation Institut fuer Medizinische Biometrie, Epidemiologie und Informatik (IMBEI), Universitaetsmedizin Mainz, Mainz, Germany

  ⨯
• Hung-Ju Lin,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

  ⨯
• Stela McLachlan,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Lena Bokemark,

  Roles Data curation, Validation

  Affiliation Wallenberg Laboratory for Cardiovascular Research, Institution for Medicin, Department for Molecular and Clinical Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden

  ⨯
• Kimmo Ronkainen,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland

  ⨯
• Mauro Amato,

  Roles Data curation, Validation

  Affiliation Centro Cardiologico Monzino, IRCCS, Milano, Italy

  ⨯
• Ulf Schminke,

  Roles Conceptualization, Data curation, Validation, Writing – review & editing

  Affiliation Department of Neurology, Greifswald University Clinic, Greifswald, Germany

  ⨯
• Sathanur R. Srinivasan,

  Roles Data curation, Validation

  Affiliation Center for Cardiovascular Health, Department of Epidemiology, Biochemistry, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America

  ⨯
• Lars Lind,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Medicine, Uppsala University, Uppsala, Sweden

  ⨯
• Shuhei Okazaki,

  Roles Data curation, Validation

  Affiliation Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan

  ⨯
• Coen D. A. Stehouwer,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Internal Medicine and Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, the Netherlands

  ⨯
• Peter Willeit,

  Roles Data curation, Methodology, Validation, Writing – review & editing

  Affiliations Department of Neurology, Medical University Innsbruck, Innsbruck, Austria, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Joseph F. Polak,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts, United States of America

  ⨯
• Helmuth Steinmetz,

  Roles Data curation, Validation

  Affiliation Department of Neurology, Goethe University, Frankfurt am Main, Germany

  ⨯
• Dirk Sander,

  Roles Data curation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Neurology, Benedictus Hospital Tutzing & Feldafing, Feldafing, Germany

  ⨯
• Holger Poppert,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Neurology, Technische Universität München, Munich, Germany

  ⨯
• Moise Desvarieux,

  Roles Data curation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Epidemiology,Mailman School of Public Health,Columbia University, New York, United States of America

  ⨯
• M. Arfan Ikram,

  Roles Data curation, Validation

  Affiliations Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands, Department of Neurology, Erasmus University Medical Center, Rotterdam, the Netherlands, Department of Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands

  ⨯
• Stein Harald Johnsen,

  Roles Data curation, Validation, Writing – review & editing

  Affiliations Department of Clinical Medicine, Uit The Arctic University of Norway, Tromsø, Norway, Department of Neurology, University Hospital of Northern Norway, Tromsø, Norway

  ⨯
• Daniel Staub,

  Roles Data curation, Validation

  Affiliation Department of Angiology, University Hospital Basel, Basel, Switzerland

  ⨯
• Cesare R. Sirtori,

  Roles Data curation, Validation

  Affiliation Center of Dyslipidemias, Niguarda Ca’ Granda Hospital, Milano, Italy

  ⨯
• Bernhard Iglseder,

  Roles Data curation, Validation

  Affiliations Parcelsus Medical University, Salzburg, Austria, Department of Geriatric Medicine, Gemeinnützige Salzburger Landeskliniken Betriebsgesellschaft GmbH Christian-Doppler-Klinik, Salzburg, Austria

  ⨯
• Oscar Beloqui,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Internal Medicine, University Clinic of Navarra, Navarra, Spain

  ⨯
• Gunnar Engström,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

  ⨯
• Alfonso Friera,

  Roles Data curation, Validation

  Affiliation Radiology Department, Hospital Universitario de la Princesa, Universidad Autónoma de Madrid, Madrid, Spain

  ⨯
• Francesco Rozza,

  Roles Data curation, Validation

  Affiliation School of Medicine, Federico II University, Naples, Italy

  ⨯
• Wuxiang Xie,

  Roles Data curation, Validation

  Affiliation Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases,Beijing Anzhen Hospital, Capital Medical University, Beijing, China

  ⨯
• Grace Parraga,

  Roles Data curation, Writing – review & editing

  Affiliation Robarts Research Institute, Western University, London, Ontario, Canada

  ⨯
• Liliana Grigore,

  Roles Data curation, Writing – review & editing

  Affiliation Centro Sisa per lo Studio della Aterosclerosi, Bassini Hospital, Cinisello Balsamo, Italy

  ⨯
• Matthieu Plichart,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Assistance Publique, Hôpitaux de Paris, Hôpital Broca, Paris, France

  ⨯
• Stefan Blankenberg,

  Roles Data curation, Writing – review & editing

  Affiliations 2nd Department of Medicine, Johannes Gutenberg-Universität, Mainz, Germany, Department of Cardiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany

  ⨯
• Ta-Chen Su,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

  ⨯
• Caroline Schmidt,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Wallenberg Laboratory for Cardiovascular Research, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Tomi-Pekka Tuomainen,

  Roles Data curation, Methodology, Writing – original draft

  Affiliation Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland

  ⨯
• Fabrizio Veglia,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft

  Affiliation Centro Cardiologico Monzino, IRCCS, Milano, Italy

  ⨯
• Henry Völzke,

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft

  Affiliations German Center for Cardiovascular Research (DZHK),partner site Greifswald, Greifswald, Germany, Institute for Community Medicine, SHIP/Clinical-Epidemiological Research, Greifswald, Germany

  ⨯
• Giel Nijpels,

  Roles Data curation, Writing – review & editing

  Affiliations Department of General Practice, VU University Medical Center, Amsterdam, the Netherlands, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands

  ⨯
• Johann Willeit,

  Roles Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft

  Affiliation Department of Neurology, Medical University Innsbruck, Innsbruck, Austria

  ⨯
• Ralph L. Sacco,

  Roles Data curation, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

  ⨯
• Oscar H. Franco,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

  ⨯
• Heiko Uthoff,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Angiology, University Hospital Basel, Basel, Switzerland

  ⨯
• Bo Hedblad,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

  ⨯
• Carmen Suarez,

  Roles Data curation, Writing – review & editing

  Affiliation Internal Medicine Department, Hospital Universitario de la Princesa, Universidad Autónoma de Madrid, Madrid, Spain

  ⨯
• Raffaele Izzo,

  Roles Data curation, Writing – review & editing

  Affiliation School of Medicine, Federico II University, Naples, Italy

  ⨯
• Dong Zhao,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases,Beijing Anzhen Hospital, Capital Medical University, Beijing, China

  ⨯
• Thapat Wannarong,

  Roles Data curation, Writing – review & editing

  Affiliations Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada, Department of Internal Medicine, Faculty of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

  ⨯
• Alberico Catapano,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft

  Affiliations IRCSS Multimedica, Milan, Italy, Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

  ⨯
• Pierre Ducimetiere,

  Roles Data curation, Writing – review & editing

  Affiliation University Paris_Sud Xi, Kremlin-Bicêtre, Le Kremlin-Bicêtre, France

  ⨯
• Christine Espinola-Klein,

  Roles Data curation, Formal analysis, Supervision, Writing – review & editing

  Affiliation 2nd Department of Medicine, Johannes-Gutenberg University, Mainz, Germany

  ⨯
• Kuo-Liong Chien,

  Roles Data curation, Validation, Writing – original draft

  Affiliation Institute of Epidemiology and Preventive Medicine, College of Public Health,National Taiwan University, Taipei, Taiwan

  ⨯
• Jackie F. Price,

  Roles Data curation, Methodology, Writing – original draft

  Affiliation Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Göran Bergström,

  Roles Data curation, Methodology, Writing – original draft

  Affiliation Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska Academy, Gothenburg University, Götheborg, Sweden

  ⨯
• Jussi Kauhanen,

  Roles Data curation, Writing – review & editing

  Affiliation Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland

  ⨯
• Elena Tremoli,

  Roles Data curation, Methodology, Resources, Writing – review & editing

  Affiliations Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy, Centro Cardiologico Monzino, IRCCS, Milano, Italy

  ⨯
• Marcus Dörr,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department B for Internal Medicine, University Medicine Greifswald, Greifswald, Germany

  ⨯
• Gerald Berenson,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medicine, Pediatrics, Biochemistry, Epidemiology, Tulane University School of Medicine and School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America

  ⨯
• Kazuo Kitagawa,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan

  ⨯
• Jacqueline M. Dekker,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands

  ⨯
• Stefan Kiechl,

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Medical University Innsbruck, Innsbruck, Austria

  ⨯
• Matthias Sitzer,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neuology, Klinikum Herford, Herford, Germany

  ⨯
• Horst Bickel,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany

  ⨯
• Tatjana Rundek,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

  ⨯
• Albert Hofman,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands

  ⨯
• Ellisiv B. Mathiesen,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Clinical Medicine, Uit The Arctic University of Norway, Tromsø, Norway

  ⨯
• Samuela Castelnuovo,

  Roles Data curation, Writing – review & editing

  Affiliation Center of Dyslipidemias, Niguarda Ca’ Granda Hospital, Milano, Italy

  ⨯
• Manuel F. Landecho,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, University Clinic of Navarra, Navarra, Spain

  ⨯
• Maria Rosvall,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

  ⨯
• Rafael Gabriel,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Escuela National de Sanidad, Instituto de Salud Carlos III, Madrid, Spain

  ⨯
• Nicola de Luca,

  Roles Data curation, Writing – review & editing

  Affiliation School of Medicine, Federico II University, Naples, Italy

  ⨯
• Jing Liu,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases,Beijing Anzhen Hospital, Capital Medical University, Beijing, China

  ⨯
• Damiano Baldassarre,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy, Centro Cardiologico Monzino, IRCCS, Milano, Italy

  ⨯
• Maryam Kavousi,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, the Netherlands

  ⨯
• Eric de Groot,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Imagelabonline & Cardiovascular, Eindhoven and Lunteren, the Netherlands, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, the Netherlands

  ⨯
• Michiel L. Bots,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

  ⨯
• David N. Yanez,

  Roles Data curation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

  ⨯
• Simon G. Thompson,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

  Affiliation Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

  ⨯
•  [ ... ],
• on behalf of the PROG-IMT study group

  ¶Complete list of the members of the PROG-IMT study group can be found in S4 Table.

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