Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia

• Ching-Hua Yeh ,

  Contributed equally to this work with: Ching-Hua Yeh, Liang-Po Hsieh

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – original draft

  Affiliations Department of Medicinal Botanicals and Health applications, Da-Yeh University, Changhua, Taiwan, Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan

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• Liang-Po Hsieh ,

  Contributed equally to this work with: Ching-Hua Yeh, Liang-Po Hsieh

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Resources, Validation, Writing – review & editing

  Affiliations Department of Medicinal Botanicals and Health applications, Da-Yeh University, Changhua, Taiwan, Department of Neurology, Cheng Ching General Hospital, Taichung, Taiwan

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• Ming-Chung Lin,

  Roles Funding acquisition, Investigation, Resources

  Affiliation Department of Anesthesiology, Chi-Mei Medical Center, Tainan, Taiwan

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• Tsui-Shan Wei,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan

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• Hui-Ching Lin,

  Roles Supervision, Writing – review & editing

  Affiliations Department and Institute of Physiology, School of Medicine, and Brain Research Center, National Yang-Ming University, Taipei, Taiwan, Neural Regenerative Medicine/Center for Neurotrauma and Neuroregeneration, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan

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• Chia-Cheng Chang,

  Roles Software, Validation

  Affiliations Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan, Department of Anesthesiology, Chi-Mei Medical Center, Tainan, Taiwan

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• Chung-Hsi Hsing

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: hsing@mail.chimei.org.tw

  Affiliations Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan, Department of Anesthesiology, Chi-Mei Medical Center, Tainan, Taiwan

  http://orcid.org/0000-0002-6091-5371

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