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Open Access
Peer-reviewed
Research Article
Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection
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Nadia Echebli,
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Nicolas Tchitchek,
Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Stéphanie Dupuy,
Roles Investigation, Methodology
Current address: Université Paris Descartes, CICB, Paris, France
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Timothée Bruel,
Roles Investigation, Methodology, Writing – review & editing
Current address: Institut Pasteur, Department of Virology, Paris, France
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Caroline Peireira Bittencourt Passaes,
Roles Methodology, Writing – review & editing
Current address: Institut Pasteur, HIV, Inflammation and Persistence Unit, Paris, France
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Nathalie Bosquet,
Roles Data curation, Formal analysis, Methodology
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Roger Le Grand,
Roles Funding acquisition, Writing – review & editing
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Christine Bourgeois,
Roles Writing – review & editing
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Benoit Favier,
Roles Writing – review & editing
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Rémi Cheynier,
Roles Data curation, Formal analysis, Methodology, Resources, Writing – review & editing
Affiliations Cytokines and Viral Infections, Immunology Infection and Inflammation Department, Institut Cochin, INSERM U1016, Paris, France, CNRS, UMR8104, Paris, France, Université Paris Descartes, Paris, France
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Olivier Lambotte,
Roles Writing – review & editing
Affiliations CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France, APHP, Service de Médecine Interne–Immunologie Clinique, Hôpitaux Universitaires Paris Sud, Le Kremlin-Bicêtre, France
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Bruno Vaslin
Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: bruno.vaslin@cea.fr
Affiliation CEA, Université Paris Sud, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA), IDMIT Department / IBFJ, Fontenay-aux-Roses, France
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Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection
- Nadia Echebli,
- Nicolas Tchitchek,
- Stéphanie Dupuy,
- Timothée Bruel,
- Caroline Peireira Bittencourt Passaes,
- Nathalie Bosquet,
- Roger Le Grand,
- Christine Bourgeois,
- Benoit Favier,
- Rémi Cheynier
- Published: January 11, 2018
- https://doi.org/10.1371/journal.pone.0190334