Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study

• David N. Naumann ,

  Contributed equally to this work with: David N. Naumann, Jon Hazeldine

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: david.naumann@nhs.net

  Affiliations Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Queen Elizabeth Hospital, Birmingham, United Kingdom, NIHR Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital, Birmingham, United Kingdom

  http://orcid.org/0000-0003-2243-2325

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• Jon Hazeldine ,

  Contributed equally to this work with: David N. Naumann, Jon Hazeldine

  Roles Data curation, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

  Affiliations NIHR Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital, Birmingham, United Kingdom, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom

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• Robert J. Dinsdale,

  Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom

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• Jon R. Bishop,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation NIHR Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital, Birmingham, United Kingdom

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• Mark J. Midwinter,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Surgery, University of Queensland, Rural Clinical School, Bundaberg, Queensland, Australia

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• Paul Harrison,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom

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• Sam D. Hutchings,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliation Department of Intensive Care Medicine, Kings College Hospital, Denmark Hill, London, United Kingdom

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• Janet M. Lord

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom

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