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Open Access
Peer-reviewed
Research Article
Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells
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Maëlle Lorvellec ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: m.lorvellec@ucl.ac.uk
Affiliations MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom, Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Federico Scottoni,
Roles Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Claire Crowley,
Roles Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Rebeca Fiadeiro,
Roles Investigation, Visualization, Writing – review & editing
Affiliations MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom, Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Panagiotis Maghsoudlou,
Roles Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Alessandro Filippo Pellegata,
Roles Methodology, Writing – review & editing
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Francesca Mazzacuva,
Roles Data curation, Writing – review & editing
Current address: William Harvey Research Institute Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
Affiliation Centre for General Omics, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Asllan Gjinovci,
Roles Investigation, Writing – review & editing
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Anne-Marie Lyne,
Roles Formal analysis, Writing – review & editing
Affiliation Institut Curie, PSL Research University, Paris, France
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Justine Zulini,
Roles Investigation, Writing – review & editing
Affiliation MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom
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Daniel Little,
Roles Resources, Writing – review & editing
Affiliation MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom
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Olukunbi Mosaku,
Roles Resources, Writing – review & editing
Affiliation MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom
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Deirdre Kelly,
Roles Funding acquisition, Supervision, Validation, Writing – review & editing
Affiliation The Liver Unit, Birmingham Children’s Hospital, Birmingham, United Kingdom
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Paolo De Coppi ,
Roles Conceptualization, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
¶‡ These authors are joint last authors on this work.
Affiliation Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Paul Gissen
Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – original draft, Writing – review & editing
¶‡ These authors are joint last authors on this work.
Affiliations MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom, Department of Stem Cells and Regenerative Medicine, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom
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Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells
- Maëlle Lorvellec,
- Federico Scottoni,
- Claire Crowley,
- Rebeca Fiadeiro,
- Panagiotis Maghsoudlou,
- Alessandro Filippo Pellegata,
- Francesca Mazzacuva,
- Asllan Gjinovci,
- Anne-Marie Lyne,
- Justine Zulini
- Published: December 20, 2017
- https://doi.org/10.1371/journal.pone.0189586