Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f

Megumi Morimoto; Yuichiro Amano; Masahiro Oka; Ayako Harada; Hisashi Fujita; Yukiko Hikichi; Ryuichi Tozawa; Masuo Yamaoka; Takahito Hara

doi:10.1371/journal.pone.0189480

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Open Access

Peer-reviewed

Research Article

Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f

Megumi Morimoto,

Roles Conceptualization, Data curation, Investigation, Writing – original draft

Affiliation Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Yuichiro Amano,

Roles Conceptualization, Data curation, Investigation, Validation

Affiliation CVM Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Masahiro Oka,

Roles Data curation, Investigation, Methodology, Validation

Affiliation CVM Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Ayako Harada,

Roles Data curation, Investigation, Methodology, Validation

Affiliation CVM Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Hisashi Fujita,

Roles Data curation, Investigation, Methodology

Affiliation DMPK Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Yukiko Hikichi,

Roles Data curation, Investigation, Methodology, Validation

Affiliation Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Ryuichi Tozawa,

Roles Project administration, Supervision

Affiliation CVM Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Masuo Yamaoka,

Roles Project administration, Supervision

Affiliation Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan
⨯
Takahito Hara

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: takahito.hara@takeda.com

Affiliation Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan

http://orcid.org/0000-0002-9941-9041

⨯

Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f

Megumi Morimoto,
Yuichiro Amano,
Masahiro Oka,
Ayako Harada,
Hisashi Fujita,
Yukiko Hikichi,
Ryuichi Tozawa,
Masuo Yamaoka,
Takahito Hara

Published: December 7, 2017
https://doi.org/10.1371/journal.pone.0189480

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