Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer’s disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid

• Kesava Asam,

  Roles Investigation

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America

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• Agnieszka Staniszewski,

  Roles Data curation, Investigation

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America

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• Hong Zhang,

  Roles Data curation, Investigation

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America

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• Scott L. Melideo,

  Roles Investigation

  Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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• Adolfo Mazzeo,

  Roles Investigation

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America

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• Michael Voronkov,

  Roles Project administration, Resources

  Affiliation Signum Biosciences, 133 Wall Street, Princeton, New Jersey, United States of America

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• Kristen L. Huber,

  Roles Investigation, Resources

  Affiliation Signum Biosciences, 133 Wall Street, Princeton, New Jersey, United States of America

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• Eduardo Pérez,

  Roles Project administration, Writing – review & editing

  Affiliation Signum Biosciences, 133 Wall Street, Princeton, New Jersey, United States of America

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• Maxwell Stock,

  Roles Conceptualization, Funding acquisition

  Affiliation Signum Biosciences, 133 Wall Street, Princeton, New Jersey, United States of America

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• Jeffry B. Stock,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America, Signum Biosciences, 133 Wall Street, Princeton, New Jersey, United States of America

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• Ottavio Arancio,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America, Department of Medicine, Columbia University, New York, NY, United States of America

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• Russell E. Nicholls

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rn95@columbia.edu

  Affiliations Department of Pathology and Cell Biology, Columbia University, New York, NY, United States of America, The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY, United States of America

  http://orcid.org/0000-0002-8964-574X

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