Interaction of porcine reproductive and respiratory syndrome virus proteins with SUMO-conjugating enzyme reveals the SUMOylation of nucleocapsid protein

Cong Wang; Nanfang Zeng; Siyu Liu; Qi Miao; Lei Zhou; Xinna Ge; Jun Han; Xin Guo; Hanchun Yang

doi:10.1371/journal.pone.0189191

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Open Access

Peer-reviewed

Research Article

Interaction of porcine reproductive and respiratory syndrome virus proteins with SUMO-conjugating enzyme reveals the SUMOylation of nucleocapsid protein

Cong Wang,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Nanfang Zeng,

Roles Data curation, Investigation

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Siyu Liu,

Roles Investigation

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Qi Miao,

Roles Investigation, Validation

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Lei Zhou,

Roles Formal analysis

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Xinna Ge,

Roles Data curation, Methodology

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Jun Han,

Roles Methodology

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Xin Guo ,

Roles Conceptualization, Funding acquisition

* E-mail: guoxin@cau.edu.cn (XG); yanghanchun1@cau.edu.cn (HY)

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China
⨯
Hanchun Yang

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: guoxin@cau.edu.cn (XG); yanghanchun1@cau.edu.cn (HY)

Affiliation Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People’s Republic of China

http://orcid.org/0000-0003-3359-3925

⨯

Interaction of porcine reproductive and respiratory syndrome virus proteins with SUMO-conjugating enzyme reveals the SUMOylation of nucleocapsid protein

Cong Wang,
Nanfang Zeng,
Siyu Liu,
Qi Miao,
Lei Zhou,
Xinna Ge,
Jun Han,
Xin Guo,
Hanchun Yang

Published: December 13, 2017
https://doi.org/10.1371/journal.pone.0189191

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SUMOylation
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Protein interactions
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Viral replication
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Small interfering RNA
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Immunoprecipitation
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Transfection
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Cytoplasm
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Protein expression
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