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Open Access
Peer-reviewed
Research Article
Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart
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Willemijn van Eldik,
Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft
Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, The Netherlands
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Brigit den Adel,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
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Jantine Monshouwer-Kloots,
Roles Data curation, Investigation
Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
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Daniela Salvatori,
Roles Formal analysis
Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Central Laboratory Animal Facility, Leiden University Medical Center, Leiden, The Netherlands
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Saskia Maas,
Roles Investigation
Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Central Laboratory Animal Facility, Leiden University Medical Center, Leiden, The Netherlands
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Ingeborg van der Made,
Roles Investigation, Methodology
Affiliation Department of Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands
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Esther E. Creemers,
Roles Resources, Supervision
Affiliation Department of Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands
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Derk Frank,
Roles Resources
Affiliation Department of Cardiology and Angiology, Universitätsklinikum Schleswig-Holstein (UKSH), University of Kiel, Kiel, Germany
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Norbert Frey,
Roles Resources, Writing – review & editing
Affiliation Department of Cardiology and Angiology, Universitätsklinikum Schleswig-Holstein (UKSH), University of Kiel, Kiel, Germany
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Nicky Boontje,
Roles Data curation, Methodology
Affiliation Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
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Jolanda van der Velden,
Roles Data curation, Formal analysis, Supervision, Writing – review & editing
Affiliation Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
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Paul Steendijk,
Roles Data curation, Formal analysis, Methodology
Affiliation Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
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Christine Mummery,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
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Robert Passier ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing
¶‡ These authors are joint senior authors on this work.
Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
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Abdelaziz Beqqali
Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Supervision, Validation, Writing – review & editing
* E-mail: a.beqqali@icloud.com
¶‡ These authors are joint senior authors on this work.
Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Department of Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands
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Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart
- Willemijn van Eldik,
- Brigit den Adel,
- Jantine Monshouwer-Kloots,
- Daniela Salvatori,
- Saskia Maas,
- Ingeborg van der Made,
- Esther E. Creemers,
- Derk Frank,
- Norbert Frey,
- Nicky Boontje
- Published: December 5, 2017
- https://doi.org/10.1371/journal.pone.0189139