BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9⁺ leukemic cells

• Marco Carretta,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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• Annet Z. Brouwers-Vos,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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• Matthieu Bosman,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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• Sarah J. Horton,

  Roles Formal analysis, Investigation, Writing – review & editing

  Current address: Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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• Joost H. A. Martens,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Molecular Biology, Faculty of Science and Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands

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• Edo Vellenga,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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• Jan Jacob Schuringa

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: j.j.schuringa@umcg.nl

  Affiliation Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  http://orcid.org/0000-0001-8452-8555

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