New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling

Klaus Dittmann; Claus Mayer; Stefan Czemmel; Stephan M. Huber; H. Peter Rodemann

doi:10.1371/journal.pone.0189087

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Open Access

Peer-reviewed

Research Article

New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling

Klaus Dittmann ,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: klaus.dittmann@uni-tuebingen.de

Affiliations Division of Radiobiology and Molecular Environmental Research, University of Tuebingen, Tuebingen, Germany, Department of Radiation Oncology, University of Tuebingen, Tuebingen, Germany, German Cancer Consortium (DKTK), partner site Tuebingen and German Cancer Research Center (DKFZ), Heidelberg, Germany

http://orcid.org/0000-0003-3433-7480

⨯
Claus Mayer,

Roles Data curation, Investigation, Methodology

Affiliations Division of Radiobiology and Molecular Environmental Research, University of Tuebingen, Tuebingen, Germany, Department of Radiation Oncology, University of Tuebingen, Tuebingen, Germany, German Cancer Consortium (DKTK), partner site Tuebingen and German Cancer Research Center (DKFZ), Heidelberg, Germany
⨯
Stefan Czemmel,

Roles Data curation, Formal analysis, Software, Validation

Affiliation Quantitative Biology Center (QBiC), University of Tuebingen, Tuebingen, Germany
⨯
Stephan M. Huber,

Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

Affiliations Department of Radiation Oncology, University of Tuebingen, Tuebingen, Germany, German Cancer Consortium (DKTK), partner site Tuebingen and German Cancer Research Center (DKFZ), Heidelberg, Germany
⨯
H. Peter Rodemann

Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

Affiliations Division of Radiobiology and Molecular Environmental Research, University of Tuebingen, Tuebingen, Germany, Department of Radiation Oncology, University of Tuebingen, Tuebingen, Germany, German Cancer Consortium (DKTK), partner site Tuebingen and German Cancer Research Center (DKFZ), Heidelberg, Germany
⨯

New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling

Klaus Dittmann,
Claus Mayer,
Stefan Czemmel,
Stephan M. Huber,
H. Peter Rodemann

Published: December 18, 2017
https://doi.org/10.1371/journal.pone.0189087

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Messenger RNA
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Immunoprecipitation
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MicroRNAs
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Protein translation
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Small interfering RNA
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Gene expression
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VEGF signaling
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