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Open Access

Peer-reviewed

Research Article

Extreme metal adapted, knockout and knockdown strains reveal a coordinated gene expression among different Tetrahymena thermophila metallothionein isoforms

Patricia de Francisco,

Roles Investigation, Writing – original draft

Affiliation Departamento de Microbiología-III, Facultad de Biología, Universidad Complutense de Madrid (UCM), Madrid, Spain
⨯
Ana Martín-González,

Roles Investigation

Affiliation Departamento de Microbiología-III, Facultad de Biología, Universidad Complutense de Madrid (UCM), Madrid, Spain
⨯
Aaron P. Turkewitz,

Roles Investigation, Writing – review & editing

Affiliation Department of Molecular Genetics and Cell Biology, Cummings Life Sciences Center, University of Chicago, Chicago, Illinois, United States of America
⨯
Juan Carlos Gutiérrez

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: juancar@bio.ucm.es

Affiliation Departamento de Microbiología-III, Facultad de Biología, Universidad Complutense de Madrid (UCM), Madrid, Spain

http://orcid.org/0000-0003-0909-3349

⨯

Extreme metal adapted, knockout and knockdown strains reveal a coordinated gene expression among different Tetrahymena thermophila metallothionein isoforms

Patricia de Francisco,
Ana Martín-González,
Aaron P. Turkewitz,
Juan Carlos Gutiérrez

x

Published: December 5, 2017
https://doi.org/10.1371/journal.pone.0189076

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Tetrahymena thermophila
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Gene expression
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Transcription factors
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Cellular stress responses
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Detoxification
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Gene regulation
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Transcriptional control
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Polymerase chain reaction
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