First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery

• Norbert Pfeiffer ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: norbert.pfeiffer@unimedizin-mainz.de

  Affiliation Dpt. of Ophthalmology, University Medical Center Mainz, Mainz, Germany

  http://orcid.org/0000-0002-5766-2617

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• Bogomil Voykov,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, University Hospital Tuebingen, Tuebingen, Germany

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• Giulia Renieri,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, Otto-von-Guericke-University, Magdeburg, Germany

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• Katharina Bell,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, University Medical Center Mainz, Mainz, Germany

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• Paul Richter,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, University Hospital Tuebingen, Tuebingen, Germany

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• Melanie Weigel,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, Otto-von-Guericke-University, Magdeburg, Germany

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• Hagen Thieme,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Dpt. of Ophthalmology, Otto-von-Guericke-University, Magdeburg, Germany

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• Barbara Wilhelm,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation STZ Eyetrial, University Hospital Tuebingen, Tuebingen, Germany

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• Katrin Lorenz,

  Roles Conceptualization, Data curation, Methodology, Validation, Writing – review & editing

  Affiliations Dpt. of Ophthalmology, University Medical Center Mainz, Mainz, Germany, SynteractHCR Deutschland GmbH, Munich, Germany

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• Martin Feindor,

  Roles Data curation, Supervision, Validation, Writing – review & editing

  Affiliation SynteractHCR Deutschland GmbH, Munich, Germany

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• Katja Wosikowski,

  Roles Data curation, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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• Michel Janicot,

  Roles Data curation, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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• Daniela Päckert,

  Roles Data curation, Formal analysis, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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• Regina Römmich,

  Roles Data curation, Formal analysis, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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• Carola Mala,

  Roles Conceptualization, Data curation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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• Petra Fettes,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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•  [ ... ],
• Eugen Leo

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Isarna Therapeutics GmbH, Munich, Germany

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