CXCR4 blockade decreases CD4⁺ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis

• Kimberly M. Ramonell,

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Wenxiao Zhang,

  Roles Formal analysis, Investigation

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Annette Hadley,

  Roles Investigation

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Ching-wen Chen,

  Roles Investigation

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Katherine T. Fay,

  Roles Investigation

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• John D. Lyons,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Nathan J. Klingensmith,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Kevin W. McConnell,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration

  Affiliation Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Craig M. Coopersmith ,

  Contributed equally to this work with: Craig M. Coopersmith, Mandy L. Ford

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliations Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America, Emory Critical Care Center, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Mandy L. Ford

  Contributed equally to this work with: Craig M. Coopersmith, Mandy L. Ford

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mandy.ford@emory.edu

  Affiliations Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America, Emory Transplant Center, Emory University School of Medicine, Atlanta, Georgia, United States of America

  http://orcid.org/0000-0001-6736-4421

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