Hypomyelinating disorders in China: The clinical and genetic heterogeneity in 119 patients

Haoran Ji; Dongxiao Li; Ye Wu; Quanli Zhang; Qiang Gu; Han Xie; Taoyun Ji; Huifang Wang; Lu Zhao; Haijuan Zhao; Yanling Yang; Hongchun Feng; Hui Xiong; Jinhua Ji; Zhixian Yang; Liping Kou; Ming Li; Xinhua Bao; Xingzhi Chang; Yuehua Zhang; Li Li; Huijuan Li; Zhengping Niu; Xiru Wu; Jiangxi Xiao; Yuwu Jiang; Jingmin Wang

doi:10.1371/journal.pone.0188869

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Open Access

Peer-reviewed

Research Article

Hypomyelinating disorders in China: The clinical and genetic heterogeneity in 119 patients

Haoran Ji,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China

http://orcid.org/0000-0001-8018-971X

⨯
Dongxiao Li,

Roles Investigation, Methodology

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Ye Wu,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Quanli Zhang,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Radiology, Peking University First Hospital, Beijing, China
⨯
Qiang Gu,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Han Xie,

Roles Investigation, Writing – review & editing

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Taoyun Ji,

Roles Funding acquisition, Investigation

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Huifang Wang,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Lu Zhao,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Haijuan Zhao,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Yanling Yang,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Hongchun Feng,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Hui Xiong,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Jinhua Ji,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Zhixian Yang,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Liping Kou,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Ming Li,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Xinhua Bao,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Xingzhi Chang,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Yuehua Zhang,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Li Li,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Huijuan Li,

Roles Investigation

Affiliations Department of Pediatrics, Peking University First Hospital, Beijing, China, Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Zhengping Niu,

Roles Resources

Affiliation Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
⨯
Xiru Wu,

Roles Resources

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
Jiangxi Xiao ,

Roles Conceptualization, Methodology, Resources, Supervision

* E-mail: wang66jm@163.com(JW); cjr.xiaojiangxi@vip.163.com(JX); jiangyw@263.net (YJ)

Affiliation Department of Radiology, Peking University First Hospital, Beijing, China
⨯
Yuwu Jiang ,

Roles Funding acquisition, Project administration, Resources, Supervision

* E-mail: wang66jm@163.com(JW); cjr.xiaojiangxi@vip.163.com(JX); jiangyw@263.net (YJ)

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
[ ... ],
Jingmin Wang

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: wang66jm@163.com(JW); cjr.xiaojiangxi@vip.163.com(JX); jiangyw@263.net (YJ)

Affiliation Department of Pediatrics, Peking University First Hospital, Beijing, China
⨯
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Hypomyelinating disorders in China: The clinical and genetic heterogeneity in 119 patients

Haoran Ji,
Dongxiao Li,
Ye Wu,
Quanli Zhang,
Qiang Gu,
Han Xie,
Taoyun Ji,
Huifang Wang,
Lu Zhao,
Haijuan Zhao

Published: February 16, 2018
https://doi.org/10.1371/journal.pone.0188869

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